Angiogenesis In Vivo Systems Part B Methods In Enzymology.php Book PDF, EPUB Download & Read Online Free

Molecular Biology of the Cell
Author: Bruce Alberts
Publisher: Garland Science
ISBN: 1317563743
Pages: 1464
Year: 2017-08-07
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
Angiogenesis: In Vivo Systems
Author: David A. Cheresh
Publisher: Academic Press
ISBN: 0080921655
Pages: 400
Year: 2009-02-12
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Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. Understanding how angiogenesis "works" and how to control it, will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis cuts across virtually every discipline. The Angiogenesis Foundation identified angiogenesis as a "common denominator" in our most serious diseases. Excessive angiogenesis occurs in diseases such as cancer, diabetic blindness, age-related macular degeneration, rheumatoid arthritis, psoriasis, and many other conditions. Insufficient angiogenesis occurs in diseases such as coronary artery disease, stroke, and delayed wound healing. * Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition. * Provides the "builder's manual" for essential techniques. This is a one-stop shop that eliminates needless searching among untested techniques. * Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics
Metastatic Cancer: Clinical and Biological Perspectives
Author: Rahul Jandial
Publisher: CRC Press
ISBN: 1587066599
Pages: 312
Year: 2013-08-08
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Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.
Anti-Angiogenesis Drug Discovery and Development
Author: Atta-ur-Rahman, Muhammad Iqbal Choudhary
Publisher: Elsevier
ISBN: 0128039647
Pages: 326
Year: 2015-06-16
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The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. These reader-friendly chapters cover topics of great scientific importance, many of which are considered significant medical breakthroughs, making this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians. Edited and written by leading experts in angiogenesis drug development Reviews recent advances in the field, such as coverage of anti-angiogenetic drugs in ovarian cancer Reports current strategies and future outlook for anti-angiogenic therapy and cardiovascular diseases
Fermented Foods in Health and Disease Prevention
Author: Juana Frías, Cristina Martínez-Villaluenga, Elena Peñas
Publisher: Academic Press
ISBN: 0128025492
Pages: 762
Year: 2016-09-12
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Fermented Foods in Health and Disease Prevention is the first scientific reference that addresses the properties of fermented foods in nutrition by examining their underlying microbiology, the specific characteristics of a wide variety of fermented foods, and their effects in health and disease. The current awareness of the link between diet and health drives growth in the industry, opening new commercial opportunities. Coverage in the book includes the role of microorganisms that are involved in the fermentation of bioactive and potentially toxic compounds, their contribution to health-promoting properties, and the safety of traditional fermented foods. Authored by worldwide scientists and researchers, this book provides the food industry with new insights on the development of value-added fermented foods products, while also presenting nutritionists and dieticians with a useful resource to help them develop strategies to assist in the prevention of disease or to slow its onset and severity. Provides a comprehensive review on current findings in the functional properties and safety of traditional fermented foods and their impact on health and disease prevention Identifies bioactive microorganisms and components in traditional fermented food Includes focused key facts, helpful glossaries, and summary points for each chapter Presents food processors and product developers with opportunities for the development of fermented food products Helps readers develop strategies that will assist in preventing or slowing disease onset and severity
Proteomics in Domestic Animals: from Farm to Systems Biology
Author: Andre Martinho de Almeida, David Eckersall, Ingrid Miller
Publisher: Springer
ISBN: 3319696823
Pages: 489
Year: 2018-02-01
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Proteomics, like other post-genomics tools, has been growing at a rapid pace and has important applications in numerous fields of science. While its use in animal and veterinary sciences is still limited, there have been considerable advances in this field in recent years, in areas as diverse as physiology, nutrition and food of animal origin processing. This is mainly as a consequence of a wider availability and better understanding of proteomics methodologies by animal and veterinary researchers. This book provides a comprehensive, state-of-the-art account of the status of farm-animal proteomics research, focusing on the principles behind proteomics methodologies and its specific applications and offering clear example.
Molecular Cell Biology
Author: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott, Kelsey Martin
Publisher: W. H. Freeman
ISBN: 1464187444
Pages: 1280
Year: 2016-06-03
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Herbal Medicine
Author: Iris F. F. Benzie, Sissi Wachtel-Galor
Publisher: CRC Press
ISBN: 1439807167
Pages: 500
Year: 2011-03-28
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The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular effects of selected herbs and their relation to clinical outcome and promotion of human health. It includes experimental approaches for looking at the bioactive components in herbs. This book also addresses the ethical challenges of using herbal medicine and its integration into modern, evidence-based medicine. Drawing from the work of leading international researchers in different fields, this volume contains an in-depth scientific examination of effects of individual herbs, as well as their use in the treatment of important diseases such as cancer, cardiovascular disease, dermatologic disorders, neurodegenerative disease, and diabetes. Due to the strong associations between oxidative stress, ageing, and disease, the powerful antioxidant properties of herbs and spices are also examined. The herbs featured are some of the most widely used remedies and cover a wide range, including flowering herbs, fruits and berries, roots and rhizomes, and fungi. The fact that composition of natural products can vary greatly and contamination and misidentification can occur are important issues in the use of herbal medicines. To help bring a new level of quality control to the production of herbal extracts, the use of mass spectrometry and chemometric fingerprinting technology is presented as a means for improved identification and authentication of herbs. As the need for effective, affordable health promotion and treatment increases, especially in the growing ageing population, there is a need for rigorous scientific examination of herbal medicines. This timely and comprehensive volume addresses this need and is an important text for medical professionals and researchers, as well as those interested in herbal or complementary medicine.
Food, Nutrition, Physical Activity, and the Prevention of Cancer
Publisher: Amer Inst for Cancer Research
Pages: 517
Year: 2007-01-01
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The Second Expert Report, Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective offers the most up-to-date recommendations for individuals and populations. They are based on the conclusions of an expert panel that certain foods, drinks and lifestyle choices protect against or lead to the development of one or more types of cancer. Additionally, the report explains how the panel reached its conclusions and what those conclusions mean to researchers, educators, practitioners and policymakers around the world. It is the largest report of its kind ever done, covering 60 exposures in relationship to 17 cancer sites. 7,000 individual studies were consulted. Book includes a CD containing the most complete bibliography and presentation of the data ever compiled.
Principles of Bone Biology
Author: John P. Bilezikian, Lawrence G. Raisz, T. John Martin
Publisher: Academic Press
ISBN: 0080568750
Pages: 1900
Year: 2008-09-29
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Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition
Regenerative Medicine and Cell Therapy
Author: J. F. Stoltz
Publisher: IOS Press
ISBN: 1614990751
Pages: 447
Year: 2012
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Most human tissues do not regenerate spontaneously. Cell therapy and tissue engineering, which involve collecting cells from either the patient or a donor and introducing them into injured tissues or organs, sometimes after modifying their properties, offer promising solutions for regenerative medicine. Indeed, so promising are these therapies that current research has shifted from organ growth to cell therapy. The range of therapeutic applications is wide, including cardiac insufficiency, atherosclerosis, cartilage defects, bone repair, burns, diabetes and liver or bladder regeneration.This book, whilst not covering all aspects
Dietary Reference Intakes for Calcium and Vitamin D
Author: Institute of Medicine, Food and Nutrition Board, Committee to Review Dietary Reference Intakes for Vitamin D and Calcium
Publisher: National Academies Press
ISBN: 0309212030
Pages: 1132
Year: 2011-03-30
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Calcium and vitamin D are essential nutrients for the human body. Establishing the levels of these nutrients that are needed by the North American population is based on the understanding of the health outcomes that calcium and vitamin D affect. It is also important to establish how much of each nutrient may be "too much." Dietary Reference Intakes for Calcium and Vitamin D provides reference intake values for these two nutrients. The report updates the DRI values defined in Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride, the 1997 study from the Institute of Medicine. This 2011 book provides background information on the biological functions of each nutrient, reviews health outcomes that are associated with the intake of calcium and vitamin D, and specifies Estimated Average Requirements and Recommended Dietary Allowances for both. It also identifies Tolerable Upper Intake Levels, which are levels above wish the risk for harm may increase. The book includes an overview of current dietary intake in the U.S. and Canada, and discusses implications of the study. A final chapter provides research recommendations. The DRIs established in this book incorporate current scientific evidence about the roles of vitamin D and calcium in human health and will serve as a valuable guide for a range of stakeholders including dietitians and other health professionals, those who set national nutrition policy, researchers, the food industry, and private and public health organizations and partnerships.
Principles of Tissue Engineering
Author: Robert Lanza, Robert Langer, Joseph P. Vacanti
Publisher: Academic Press
ISBN: 0123983703
Pages: 1936
Year: 2013-10-17
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Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout
Biomaterials Science
Author: Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen, Jack E. Lemons
Publisher: Academic Press
ISBN: 008087780X
Pages: 1573
Year: 2012-12-31
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The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: "the only such text that currently covers this area comprehensively" - Materials Today Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank
Zinc Signaling in Physiology and Pathogenesis
Author: Toshiyuki Fukada, Taiho Kambe
Publisher: MDPI
ISBN: 3038428213
Pages: 292
Year: 2018-05-04
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This book is a printed edition of the Special Issue "Zinc Signaling in Physiology and Pathogenesis" that was published in IJMS